LGD4033 10 (Ligandrol) is a popular SARM (selective androgen receptor modulator), allowing those who use it to avoid the potential steroid-caused hormonal side effects and can be utilized by bodybuilders, endurance athletes, sporting athletes, and even physique models. LGD4033 10 (Ligandrol) clinical trials on humans have shown a great increase in muscle mass and strength without the gaining of fat which makes it great for a range of people pursuing various goals from bulking and cutting to improving recovery speed and improving body composition. The achieved results are topped by improvements in bone mineral density, bone strength, and less muscle wasting.
Medical doses used in clinical trials of LGD4033 10 (Ligandrol) are in the 0.5mg to 2mg daily range. However even at 1mg daily dose strong testosterone suppression already occurs.
Beginners are suggested to start with 1mg daily, advanced users can go for 5-10mg daily and the most advanced athletes and bodybuilders are known to increase these dosages up to 15-20mg daily, while for women the maximal recommended daily dosage is 5mg. With administration happening once or twice a day, due to a long half-life time of 24-36 hours for an 8-12 weeks cycle, followed by a 4 week PCT afterward.
During the conducted human clinical trials on LGD4033 10 (Ligandrol), no serious adverse effects were noted and the drug was considered to be well tolerated. The main concern is significant testosterone and mild other hormone suppression, which can be treated with PCT.
Mild side effects may include headache, nausea, fatigue, and HDL decrease.
While LGD 4033 should not cause HPTA shutdown (Testosterone production shutdown) like many steroids, it can still cause major suppression of testosterone in some athletes. On Reddit, many users are reporting Testosterone levels of 200-300 ng/dl after LGD4033 cycles. The only way to tell whether or not you need to take PCT (like Tamoxifen) after a SARM cycle is to conduct a blood test and confirm your testosterone, LH, and FSH levels. Low LH and FSH will indicate that your HPTA is suppressed (and additional lower levels of Testosterone will confirm this claim).
It is recommended to buy PCT compounds (like Tamoxifen or Clomiphene) before you buy your SARMs. Compounds like Tamoxifen are very affordable and are always good to have just in case you will need to PCT.
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